Chinaberry Bark (Meliae Cortex) in TCM: Benefits, Uses, and More

• Research shows that the Chinese herbal medicine Ku Lian Pi (Chinaberry Bark) might help get rid of parasites, fight cancer, and kill pests. But people still argue about how well it works and whether it’s safe.
• It seems to be commonly used to treat gut parasites like roundworms, hookworms, and whipworms. People also use it on the skin for things like scabies and ringworm.
• There are some risks, though. It can be toxic, so certain groups should avoid it—pregnant women, people with liver or heart problems, those with stomach ulcers, or anyone who’s physically weak.
• In Western countries, Ku Lian Pi isn’t used much. Scientists there are mainly studying its potential as a cancer treatment in alternative and complementary medicine.

If you’ve ever wondered about the hidden gems of Traditional Chinese Medicine (TCM), Chinaberry Bark—known as Ku Lian Pi (苦楝皮) or Meliae Cortex—might catch your attention. This herb, derived from the bark of the Chinaberry tree (Melia azedarach L.) or Toosendan tree (Melia toosendan Sieb. et Zucc.), has been a go-to remedy in TCM for centuries. Celebrated for tackling pesky parasites and soothing itchy skin, it’s a powerhouse with a catch: it’s toxic if not used wisely.

Curious? Let’s dive into what makes Chinaberry Bark special, how it’s used, and what you need to watch out for.

What Is Chinaberry Bark?

Picture a tree thriving across Asia, its bark peeled and dried to become a staple in TCM. That’s Chinaberry Bark, sourced from the roots or trunk of Melia azedarach or Melia toosendan. In TCM, it’s classified as an “Herb that Expels Parasites,” with a bitter taste, cold nature, and a touch of toxicity¹. It targets the liver, spleen, and stomach meridians, making it a key player for clearing heat, drying dampness, and kicking parasites to the curb. Harvested in spring or fall, the bark is scrubbed clean, sliced, and either used fresh or dried for later².

But here’s the kicker: while it’s a traditional favorite, its potency comes with risks. Let’s explore what it can do—and what to avoid.

Proven Benefits of Chinaberry Bark

Chinaberry Bark isn’t just folklore; it’s backed by both tradition and some modern science. Here’s what it brings to the table:

• Antiparasitic Powerhouse: Think of it as a bouncer for your gut. It’s especially effective against intestinal parasites like roundworms, hookworms, and pinworms³. Research shows compounds like toosendanin can paralyze these critters, helping your body flush them out. One study found that Melia toosendan extracts work wonders against parasites in lab settings (Insecticidal activity of Melia toosendan extracts).
• Insect-Repelling Magic: Beyond your body, Chinaberry Bark doubles as a natural bug zapper. Its insecticidal properties—thanks to toosendanin—make it a traditional choice for keeping pests away from crops and skin alike⁴.
• Potential Cancer Fighter: Here’s where it gets exciting. Early studies suggest that Melia Bark might have anticancer chops⁵. Compounds in the bark have shown promise in killing off cancer cells—like those in liver or colon cancer—by triggering cell death. While it’s not ready for prime time, this is a hot topic in research (Anticancer effects of Melia toosendan).
• Bone Health Bonus: A 2023 study hinted that Chinaberry Bark could help fend off osteoporosis by supporting bone metabolism. It’s a long shot from being a standard treatment, but it’s an intriguing perk (Anti-osteoporotic compound from Melia toosendan).

These benefits sound impressive, right? But don’t rush to your herbalist just yet—its toxic side demands respect.

Summary: Chinaberry Bark has various benefits. It’s an antiparasitic, insect-repelling, shows potential against cancer and may aid bone health. But it’s toxic, so use with caution.

How Is Chinaberry Bark Used in TCM?

In TCM, Chinaberry Bark is a versatile tool for battling parasites and skin woes. Here’s how it’s traditionally prepped and applied:

Kicking Out Parasites

• Roundworms, Hookworms, and Pinworms: A classic use! It’s often boiled into a decoction—6–9 grams of dried bark or 15–30 grams of fresh—taken solo or teamed up with herbs like Areca Seed (Bing Lang) for extra oomph. For pinworms, it’s mixed with Stemona Root (Bai Bu) and Mume Fruit (Wu Mei) into a concentrated enema, used nightly for 2–4 days⁶.
• Special Cases: Kids with roundworm-related bowel blockages? A 25% decoction enema might do the trick. For biliary ascariasis (worms in the bile ducts), a 100% fresh bark decoction has shown results⁷.

Soothing Skin Troubles

• Scabies, Tinea, and Eczema: Its bitter, cooling vibe tackles heat and dampness, easing itching and inflammation. Grind it into a powder, mix with vinegar or pig fat, and dab it on. Or, brew a decoction to wash the affected area—simple yet effective⁸.

Beyond the Basics

Some TCM practitioners use it for viral infections or inflammation, though evidence here is thinner. It’s a bit like a Swiss Army knife—handy, but you need to know how to wield it⁹.

Quick Guide: Chinaberry Bark Uses in TCM

Summary: In TCM, Chinaberry Bark is used to fight parasites like roundworms, hookworms, pinworms, etc. It can be made into decoctions or enemas. It also soothes skin problems. Some use it for viral issues, though evidence is limited.

Risks and Safety Warnings

Before you get too excited, let’s talk about the elephant in the room: Chinaberry Bark is toxic. Here’s what you need to know:

• Toxicity Troubles: Overdo it, and you might face dizziness, nausea, or stomach pain. In serious cases, it can lead to breathing issues, internal bleeding, liver damage, or worse.Think of it like a strong spice—a little adds flavor, too much ruins the dish¹⁰.
• Who Should Avoid It¹¹:
  • Pregnant women (it’s a hard no)
  • People with liver or heart conditions
  • Those with peptic ulcers
  • Anyone with a weak stomach or spleen deficiency
• Dosage Matters: Stick to 6–9 grams dried or 15–30 grams fresh daily¹², and don’t use it long-term. Its active ingredients are tough to extract, so simmer it slowly over low heat.

Pro Tip: Never DIY with Meliae Cortex. Consult a TCM practitioner or doctor to keep it safe.

Summary: Before getting excited, note that Chinaberry Bark is toxic. Overdosing can cause various problems. Pregnant women and those with certain conditions should avoid it. Stick to proper dosage and don’t DIY; consult a TCM expert or doctor.

Chinaberry Bark in the West

Across the pond, Chinaberry Bark isn’t a household name. Western medicine leans on safer antiparasitic drugs, leaving Ku Lian Pi on the sidelines. That said, researchers are intrigued by its anticancer potential—studies like one on cytotoxic compounds in Melia toosendan bark hint at future possibilities (Cytotoxic tirucallane triterpenoids). For now, it’s more of a lab curiosity than a pharmacy staple.

Q&A

Q: Can kids use Chinaberry Bark safely?

A: Yes, but only under a pro’s watch. Its toxicity makes it tricky, so low doses are key for parasite treatment in little ones¹³.

Q: Is it good for DIY skin remedies?

A: Sure, for external use like scabies or tinea—just prep it right (powder or wash) and test a small patch first. Still, check with an expert¹⁴.

Q: How does it stack up against other parasite herbs?

A: Compared to Areca Seed (Bing Lang), Chinaberry Bark packs a stronger punch against worms but brings more risk. It’s a trade-off between power and safety.

The Bottom Line

Chinaberry Bark (Meliae Cortex) is like a double-edged sword in TCM—sharp enough to cut through parasites and skin issues, but risky if mishandled. Its antiparasitic prowess, insect-repelling skills, and emerging cancer-fighting potential make it fascinating, yet its toxicity keeps it in check. Whether you’re exploring TCM or just curious about natural remedies, one thing’s clear: this herb demands respect and expert guidance.

So, next time you hear about Ku Lian Pi, you’ll know it’s a heavy hitter—not to be taken lightly.

Trusted Source

1. https://baike.baidu.com/item/%E8%8B%A6%E6%A5%9D%E7%9A%AE/903422 ↩︎
2. http://www.zysj.com.cn/zhongyaocai/kulianpi/index.html ↩︎
3. 王永祥,孙怀宝,路步炎.使君子,苦楝皮及榧子驱治肠蛔虫的报告[J].山东医药, 1957(5):19-22. ↩︎
4. 程玮,肖啸,严达伟,等.云南苦楝皮成分的分离鉴定及其对猪蛔虫成虫及虫卵的离体毒理研究[J].山东畜牧兽医, 2008(10):4.DOI:10.3969/j.issn.1007-1733.2008.10.001. ↩︎
5. 王进.川楝素诱导肿瘤细胞凋亡的分子机制[D].重庆医科大学,2010.DOI:10.7666/d.Y1731255. ↩︎
6. https://zhongyibaike.com/amp/%E8%8B%A6%E6%A5%9D%E7%9A%AE ↩︎
7. https://www.dayi.org.cn/cmedical/301593 ↩︎
8. 刘海燕.一种苦楝皮中药治皮肤瘙痒症泡腾片:CN201410527312.8[P].CN105560631A[2025-03-13]. ↩︎
9. https://patents.google.com/patent/CN102266389B/zh ↩︎
10. Forrester M B, Layton G M, Varney S M. Melia azedarach ingestions reported to Texas poison centers[J]. The Journal of Emergency Medicine, 2020, 58(4): e179-e184. https://www.sciencedirect.com/science/article/pii/S0736467920300135 ↩︎
11. https://m.baidu.com/bh/m/detail/ar_4196925635220980993(Zhang Ting, Deputy Chief Physician, Department of Integrative Chinese and Western Medicine, Third Xiangya Hospital of Central South University) ↩︎
12. http://www.a-hospital.com/w/%E8%8B%A6%E6%A5%9D%E7%9A%AE ↩︎
13. https://m.zyctd.com/gongxiao95.html ↩︎
14. https://m.baidu.com/bh/m/detail/sv_5992824371322619145(Yang Xiaobing, Deputy Chief Physician, Department of Traditional Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine) ↩︎