Medicinal Plants: What Are They, History and Classification Guide

For millennia, humans have turned to nature for healing. Medicinal plants, also known as herbs, have been integral to traditional medicine practices across the globe, predating recorded history¹.

These plants synthesize a vast array of compounds, serving functions like defense against insects, fungi, and herbivores².

Many of these phytochemicals possess potential or established bioactivity, leading to the development of numerous modern medicines³.

So, let’s embark on a journey around the world, exploring the rich tapestry of medicinal plants and their traditional uses.

A Historical Glimpse into Herbal Medicine

The earliest documented use of medicinal plants dates back to the Sumerian civilization, where clay tablets listed hundreds of remedies, including opium⁴. The ancient Egyptians, documented in the Ebers Papyrus, described over 850 plant-based medicines⁵.

Dioscorides, in his “De Materia Medica,” cataloged over 600 medicinal plants and 1,000 formulations, laying the foundation for pharmacopoeias for nearly 1,500 years⁶. This historical reliance on plants underscores their enduring significance in human health.

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The Science Behind the Herbs

Modern drug research often utilizes ethnobotany—the study of traditional plant use—to identify pharmacologically active substances in nature⁷.

This approach has led to the discovery of crucial compounds like aspirin (from willow bark)⁸, digoxin (from foxglove)⁹, quinine (from cinchona bark)¹⁰, and opium (from the opium poppy)¹¹.

These compounds typically fall into four main biochemical categories:

1. Alkaloids: Nitrogen-containing compounds with potent physiological effects (e.g., morphine, caffeine)¹².
2. Glycosides: Sugar-bound compounds with diverse actions (e.g., digoxin)¹³.
3. Polyphenols: Antioxidant-rich compounds (e.g., flavonoids, tannins)¹⁴.
4. Terpenes: Aromatic compounds with various properties (e.g., essential oils)¹⁵.

Summary: Modern medicine discovers plant-based drugs like aspirin and digoxin by studying traditional herbal uses. These natural compounds fall into four key groups—alkaloids, glycosides, polyphenols, and terpenes—each offering unique medicinal benefits, from pain relief to antioxidants.

A Global Tour of Traditional Herbal Practices

Medicinal plants remain crucial in non-industrialized societies due to their accessibility and affordability compared to modern pharmaceuticals. Here’s a brief overview of traditional herbal medicine across different regions:

Africa: A Deeply Rooted Tradition

• History and Prevalence: Traditional African medicine, predating Western medicine, is interwoven with cultural practices and spiritual beliefs. Up to 80% of the African population relies on it for primary healthcare¹⁶.
• Common Herbs: Well-known plants include geranium (for respiratory issues), aloe vera (for digestive problems), and Artemisia annua (source of the antimalarial artemisinin).¹⁷
• Applications: African herbal medicine addresses physical and mental health, treating conditions like malaria, HIV/AIDS, and various chronic diseases¹⁸.
• Historical Records: Knowledge is primarily passed down orally, though historical references exist in ancient healers’ practices and archaeological finds in ancient Egypt.
• Modern Research: There’s growing interest in scientifically validating traditional therapies, such as research on Artemisia annua for malaria¹⁹.

India: The Ancient Wisdom of Ayurveda

• History and Prevalence: Ayurveda, one of the oldest known medical systems, has been practiced for over 5,000 years, with texts like the Charaka Samhita documenting its methods²⁰.
• Common Herbs: Turmeric (Curcuma longa), ashwagandha (Withania somnifera), and neem (Azadirachta indica) are among the most frequently used.
• Applications: Ayurveda treats a wide range of ailments, from digestive issues to skin conditions, emphasizing balancing the body’s doshas (vital energies)²¹.
• Historical Records: Ancient texts like the Sushruta Samhita provide detailed descriptions of medicinal plants, surgical procedures, and therapies²².
• Modern Research: Extensive research explores the efficacy of Ayurvedic herbs, with some compounds adapted into modern medicines²³.

China: The Comprehensive System of Traditional Chinese Medicine (TCM)

• History and Prevalence: TCM, with a history spanning over 2,000 years, is based on foundational texts like the Huangdi Neijing (The Yellow Emperor’s Inner Classic) from the 3rd century BCE²⁴.
• Common Herbs: Ginseng (Panax ginseng), goji berry (Lycium barbarum), and astragalus (Astragalus membranaceus) are central to TCM.
• Applications: TCM uses herbs for holistic health management, covering internal medicine, gynecology, and pediatrics²⁵.
• Historical Records: Classic works like the Shennong Ben Cao Jing (The Classic of Herbal Medicine) detail a vast array of herbs and their uses²⁶.
• Modern Research: China leads in herbal research, with extensive studies on herbs like artemisinin (for malaria)²⁷ and ephedra (for respiratory problems, though with noted safety concerns)²⁸.

Roman and European Traditions: A Legacy of Herbal Knowledge

• History and Prevalence: In ancient Rome, herbal medicine was integrated into daily life, influenced by Greek and later by Arab scholarship.
• Common Herbs: Plants like fennel (Foeniculum vulgare), rosemary (Rosmarinus officinalis), and chamomile (Matricaria chamomilla) hold historical significance²⁹.
• Applications: Used for various conditions from digestive issues to pain relief, some herbs are still used in modern phytotherapy (herbal medicine)³⁰.
• Historical Records: Texts like Dioscorides’ “De Materia Medica” documented the widespread use of plants³¹.
• Modern Research: Research on European herbs continues, with many traditional remedies influencing contemporary herbal products.

The Americas: Indigenous Herbal Practices

• History and Prevalence: Indigenous American herbal medicine predates European contact, with diverse practices among different tribes³².
• Common Herbs: Echinacea (Echinacea purpurea), white willow (Salix alba), and sage (Salvia officinalis) are significant, with some, like cinchona, providing quinine.
• Applications: Used for everything from wound healing to spiritual purification, often integrated into shamanic practices.
• Historical Records: Records come from colonial observations, Indigenous oral traditions, and archaeological evidence.
• Modern Research: There’s growing interest in North American native plants for modern medicine, particularly in areas like anti-inflammatory and immune support³³.

Summary: Traditional medicine across Africa, India, China, Europe, and the Americas has deep historical roots, using local herbs like aloe vera, turmeric, and ginseng to treat various ailments. Passed down through generations, these practices are now being studied scientifically for modern healthcare applications.

The Global Market and Regulatory Landscape

The global market for plant-derived extracts and pharmaceuticals is estimated to be worth hundreds of billions of dollars³⁴.

While regulation of traditional medicine varies across countries, the World Health Organization (WHO) coordinates efforts to promote safe and rational use³⁵.

Medicinal plants face threats like climate change, habitat destruction, and over-harvesting to meet market demands³⁶.

Bottom line

From ancient civilizations to modern research, medicinal plants have played a vital role in human health. Their continued use in traditional medicine and their contribution to modern pharmaceuticals highlight their enduring importance. As we move forward, it’s crucial to balance the use of these valuable resources with conservation efforts to ensure their availability for future generations.

Trusted source

1. https://www.mdpi.com/2813-2998/3/1/11 ↩︎
2. https://zh.wikipedia.org/zh-cn/%E8%8D%AF%E7%94%A8%E6%A4%8D%E7%89%A9#:~:text=%E8%8D%AF%E7%94%A8%E6%A4%8D%E7%89%A9%E4%B9%9F%E8%A2%AB,%E7%94%98%E8%8D%89%EF%BC%9A%E4%BD%9C%E4%B8%BA%E4%B8%AD%E8%8D%AF%E7%94%A8%E9%80%94%E5%B9%BF%E6%B3%9B%E3%80%82 ↩︎
3. https://scholar.google.com/scholar_url?url=https://www.scirp.org/journal/paperinformation.aspx%3Fpaperid%3D59593&hl=zh-CN&sa=X&ei=PmiSZ5GGA8-Z6rQP7ceryQ8&scisig=AFWwaeZlyMC6-W7yGpzNIPYu10mw&oi=scholarr ↩︎
4. https://www.chimia.ch/chimia/article/download/5809/5099/15784 ↩︎
5. https://pmc.ncbi.nlm.nih.gov/articles/PMC8459052/#:~:text=The%20famous%20Ebers%20Papyrus%20has,species)%20to%20make%20876%20prescriptions%20( ↩︎
6. https://en.wikipedia.org/wiki/De_materia_medica#:~:text=The%20work%20presents%20about%20600,medicines%20made%20from%20these%20sources. ↩︎
7. https://pmc.ncbi.nlm.nih.gov/articles/PMC10494464/ ↩︎
8. https://en.wikipedia.org/wiki/History_of_aspirin ↩︎
9. https://pmc.ncbi.nlm.nih.gov/articles/PMC11033962/ ↩︎
10. https://journals.sagepub.com/doi/abs/10.1177/0141076816688411 ↩︎
11. https://www.nature.com/articles/s41598-018-20996-9 ↩︎
12. https://www.britannica.com/science/alkaloid ↩︎
13. https://pharmanotes.org/2021/04/glycoside-classification/ ↩︎
14. https://www.sciencedirect.com/science/article/pii/B9780128135723000014 ↩︎
15. https://pmc.ncbi.nlm.nih.gov/articles/PMC9039924/ ↩︎
16. https://pmc.ncbi.nlm.nih.gov/articles/PMC4651463/ ↩︎
17. https://pmc.ncbi.nlm.nih.gov/articles/PMC4311864/#:~:text=In%20the%201970s%2C%20artemisinin%20was,from%20the%20plant%20Artemisia%20annua. ↩︎
18. https://www.afro.who.int/health-topics/traditional-medicine ↩︎
19. https://www.pnas.org/doi/10.1073/pnas.1413127112#:~:text=annua%20plant%20as%20a%20malaria,rodent%20malaria%20model%20(9). ↩︎
20. https://en.wikipedia.org/wiki/Ayurveda ↩︎
21. https://pmc.ncbi.nlm.nih.gov/articles/PMC10972801/#:~:text=The%20Ayurvedic%20approach%20to%20clinical,Dosha%20(regulatory%20functional%20factors%20of ↩︎
22. https://pmc.ncbi.nlm.nih.gov/articles/PMC11527508/ ↩︎
23. https://www.scuhs.edu/front-page-news/atp-efficacy-of-ayurveda/ ↩︎
24. https://pmc.ncbi.nlm.nih.gov/articles/PMC2287209/ ↩︎
25. https://clinic.acumedic.com/can-we-help/condition/womens-health-gynaecology/#:~:text=According%20to%20Chinese%20Medicine%20theory,issues%20and%20other%20co%2Dmorbidities. ↩︎
26. https://www.researchgate.net/publication/320146361_The_first_Materia_Medica_The_Shen_Nong_Ben_Cao_Jing ↩︎
27. https://www.ncbi.nlm.nih.gov/books/NBK1713/ ↩︎
28. https://pubmed.ncbi.nlm.nih.gov/14563905/ ↩︎
29. https://www.nccih.nih.gov/health/chamomile#:~:text=Chamomile%20was%20described%20in%20ancient,Egypt%2C%20Greece%2C%20and%20Rome. ↩︎
30. https://www.ncbi.nlm.nih.gov/books/NBK92773/#:~:text=Plants%2C%20herbs%2C%20and%20ethnobotanicals%20have,for%20health%20promotion%20and%20treatment ↩︎
31. https://www.loc.gov/item/2021666851/#:~:text=During%20the%20first%20century%2C%20the,very%20important%20document%20on%20botany ↩︎
32. https://www.nlm.nih.gov/nativevoices/exhibition/healing-ways/medicine-ways/healing-plants.html ↩︎
33. https://www.researchgate.net/publication/12399887_Inflammation_and_Native_American_medicine_The_role_of_botanicals ↩︎
34. https://www.bccresearch.com/market-research/biotechnology/botanical-and-plant-derived-drugs-global-markets.html#:~:text=The%20global%20market%20for%20botanical,a%20compound%20annual%20growth%20rate ↩︎
35. https://www.who.int/news-room/questions-and-answers/item/traditional-medicine#:~:text=The%20WHO%20traditional%20medicine%20programme,Unit%2C%20WHO%20is%20working%20with ↩︎
36. https://www.britishecologicalsociety.org/medicinal-plants-and-unsustainable-harvesting-a-closer-look/ ↩︎