Atractylodes lancea (Cang Zhu)

Atractylodes lancea (Cang Zhu): What It Is, Benefits, and Risks

Atractylodes lancea (Cang Zhu) stands as a testament to the enduring wisdom of Traditional Chinese Medicine, offering a blend of benefits that cater to digestive health, immune support, and beyond.

In the vast world of herbal medicine, few plants boast the rich history and multifaceted applications of Atractylodes lancea, commonly known as Cang Zhu. Originating from Traditional Chinese Medicine (TCM), Cang Zhu has been revered for centuries for its therapeutic properties.

But what exactly is Cang Zhu, and why is it gaining attention in modern wellness circles?

Let’s delve into the roots of this remarkable herb, uncover its benefits, and explore the potential risks associated with its use.

Atractylodes lancea (Cang Zhu)

What is Atractylodes lancea (Cang Zhu)?

Atractylodes japonica
image: Wikimedia Commons

Atractylodes lancea, or Cang Zhu, is a perennial herb belonging to the Asteraceae family1. Primarily cultivated in regions like Jiangsu, Henan, Hebei, Shanxi, and Shaanxi in China, the plant’s dried rhizomes are the prized parts used in medicinal preparations. With its distinctive gray-brown surface adorned with wrinkles and remnants of root hairs, Cang Zhu is as intriguing in appearance as it is in application2.

In TCM, Cang Zhu is categorized as a warm and bitter herb. It’s traditionally used to dry dampness, strengthen the spleen, dispel wind and cold, and brighten the eyes3. These attributes make it a versatile remedy for a variety of ailments, from digestive issues to respiratory conditions.

Now, we not only use its root, but also use its extract, which is more convenient and simple.

Health benefits and medical uses

Cang Zhu’s reputation is built on a foundation of both traditional wisdom and emerging scientific research. Here are some of the notable benefits associated with this herbal powerhouse:

1. Digestive Health

One of the primary uses of Cang Zhu in TCM is to promote digestive function. It aids in alleviating symptoms like abdominal bloating, loss of appetite, and diarrhea by strengthening the spleen and drying excess dampness4. Modern studies have corroborated these effects, highlighting Cang Zhu’s ability to enhance gastric motility and stimulate appetite5.

2. Anti-Inflammatory and Immune Support

Cang Zhu contains β-eudesmol, a compound known for its anti-inflammatory properties6. This makes it effective in reducing inflammation-related pain and swelling, particularly in conditions like rheumatoid arthritis and asthma7. Additionally, its antimicrobial properties help bolster the immune system, making the body more resilient against infections8.

3. Antimicrobial and Antiviral Effects

Research indicates that the volatile oils in Cang Zhu exhibit significant antibacterial and antifungal activities9. They’ve been shown to inhibit the growth of pathogens like E. coli, Staphylococcus aureus, and even HIV and H3N2 influenza viruses10. This antimicrobial prowess underscores Cang Zhu’s traditional use in disinfecting environments and preventing infections11.

4. Cardiovascular and Liver Health

Cang Zhu has a mild regulatory effect on the cardiovascular system, helping to balance blood pressure and support heart function12. Moreover, its hepatoprotective properties aid in preventing liver damage, promoting protein synthesis in the liver, and protecting liver cells from toxins13.

5. Blood Sugar Regulation

Emerging studies suggest that Cang Zhu can lower blood glucose levels, making it a potential ally for those managing diabetes14. It achieves this by inhibiting glycogen synthesis and reducing glucose production, thereby helping to maintain stable blood sugar levels15.

Atractylodes lancea has become an important herb in traditional Chinese medicine and modern scientific research due to its various effects such as promoting digestion, anti-inflammatory immunity, antibacterial and antiviral, protecting cardiovascular and liver health, and regulating blood sugar.

Atractylodes Lancea source: douyin ID 345351919

Risks and Side Effects

While Cang Zhu offers numerous health benefits, it’s essential to approach its use with awareness of potential risks16:

1. Dryness and Dehydration

Given its drying properties, excessive use of Cang Zhu can lead to dry mouth, throat irritation, and dehydration. Individuals should monitor their intake to avoid these uncomfortable side effects.

2. Neurological Symptoms

High doses of Cang Zhu may induce nervous system disturbances such as dizziness, headaches, and in severe cases, neurological toxicity. Symptoms akin to atropine poisoning, like flushed skin and blurred vision, have also been reported.

3. Respiratory Suppression

Cang Zhu contains compounds that can depress the respiratory system. Overconsumption might result in rapid or shallow breathing, posing risks, especially for those with pre-existing respiratory conditions.

4. Cardiovascular Effects

While beneficial in moderation, large doses of Cang Zhu can lead to blood pressure fluctuations, including hypotension (low blood pressure), which might be dangerous for individuals with cardiovascular issues.

5. Blood Sugar Levels

Its blood sugar-lowering effects can be a double-edged sword. Those prone to hypoglycemia or already managing low blood sugar should exercise caution, as Cang Zhu might exacerbate their condition.

Cang Zhu has health benefits but can cause dryness, neurological symptoms, respiratory suppression, cardiovascular effects, and blood sugar issues if used excessively or improperly.

How to Use it

Cang Zhu is available in various forms, including dried roots, powders, extracts, and capsules. The traditional method involves decocting the dried rhizomes in water to create a medicinal tea. The recommended dosage typically ranges from 3 to 9 grams per day17. However, it’s crucial to consult with a healthcare professional before incorporating Cang Zhu into your regimen, especially if you’re pregnant, nursing, or on medication18.

Modern Research

Modern scientific research has begun to unravel the complexities of Cang Zhu’s pharmacological actions. Studies have validated its anti-inflammatory, antimicrobial, and antioxidant properties, supporting its traditional uses. However, much of the current evidence is preliminary, and more clinical trials are needed to fully understand its efficacy and safety profile19.

Frequently Asked Questions (FAQ)

Q1: Can Cang Zhu be used alongside conventional medications?

A1: It’s essential to consult with a healthcare professional before combining Cang Zhu with other medications, as interactions may occur20, especially with drugs that affect blood sugar or blood pressure.

Q2: How long does it take to experience the benefits of Cang Zhu?

A2: Effects can vary based on the individual’s condition and the form of Cang Zhu used. Some may notice improvements in digestion within a few days, while other benefits might take longer.

Q3: Is Cang Zhu safe for long-term use?

A3: While generally considered safe when used appropriately, long-term use should be monitored by a healthcare provider to prevent potential side effects like dehydration or blood sugar imbalances21.

Bottom line

Atractylodes lancea (Cang Zhu) stands as a testament to the enduring wisdom of Traditional Chinese Medicine, offering a blend of benefits that cater to digestive health, immune support, and beyond. While its therapeutic potential is impressive, it’s imperative to approach its use with caution and awareness of the possible risks. As with any herbal supplement, consulting with a healthcare provider ensures that you harness its benefits safely and effectively.

Trusted source

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  3. https://www.cmro.gov.hk/html/b5/useful_information/public_health/publication/AdverseEvents25.html ↩︎
  4. http://szyyj.gd.gov.cn/zyyfw/ysbj/content/post_4411770.html ↩︎
  5. https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1518433/abstract ↩︎
  6. https://pubmed.ncbi.nlm.nih.gov/33449412/ ↩︎
  7. ZHANG Ming-fa, SHEN Ya-qin. Advances in studies on anti-inflammation, antitumor, and immunoregulation of Atractylodis Rhizoma[J]. Drug Evaluation Research, 2016, 39(5): 885-890. ↩︎
  8. https://www.sciencedirect.com/science/article/pii/S1995764514600699 ↩︎
  9. https://www.researchgate.net/publication/41410647_Antimicrobial_activity_of_volatile_oil_from_Atractylodes_lancea_against_three_species_of_endophytic_fungi_and_seven_species_of_exogenous_fungi ↩︎
  10. https://pmc.ncbi.nlm.nih.gov/articles/PMC8320351/ ↩︎
  11. 徐小平, 李卓成, 肖建德, 等. 苍术消毒剂杀菌性能的实验观察[J]. 中华医院感染学杂志, 2003, 13(9): 843-844. ↩︎
  12. https://onlinelibrary.wiley.com/doi/10.1155/2017/5929234 ↩︎
  13. https://pubmed.ncbi.nlm.nih.gov/39391981/ ↩︎
  14. https://cmjournal.biomedcentral.com/articles/10.1186/s13020-018-0216-7 ↩︎
  15. https://pmc.ncbi.nlm.nih.gov/articles/PMC11535289/ ↩︎
  16. https://m.baidu.com/bh/m/detail/ar_10713192774157218476(Sun Lianqing, Chief Physician, Department of Traditional Chinese Medicine, The First Affiliated Hospital of Xi’an Jiaotong University) ↩︎
  17. https://yibian.hopto.org/db/?yno=8 ↩︎
  18. Hu Shilin. Research on Materia Medica of Atractylodes Atractylodes [J]. Chinese Medical Journal, 2001, 16 (1): 11-13. MLA ↩︎
  19. [1]杜毅,赵丽蓉,高华,等.苍术的化学成分与现代药理研究综述[J].内蒙古中医药, 1998(S1):2.DOI:CNKI:SUN:NZYY.0.1998-S1-161. ↩︎
  20. https://link.springer.com/article/10.1007/s11104-020-04615-z ↩︎
  21. https://www.webmd.com/vitamins/ai/ingredientmono-1097/atractylodes ↩︎
Michael Zhang
Michael Zhang

Michael Zhang is a long-time health buff. He's committed to a lifestyle that's rooted in science. You can count on his articles to be accurate and reliable.

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