Fangji (Fourstamen Stephania Root)

Fangji (Fourstamen Stephania Root): What It Is, Benefits, and Risks

Fangji, also known as Fourstamen Stephania Root, is a traditional herbal remedy that has been used in Chinese medicine for centuries.

Fangji, also known as Fourstamen Stephania Root, is a traditional herbal remedy that has been used in Chinese medicine for centuries. Known for its unique properties and applications, it has gained attention for its potential health benefits, as well as its associated risks.

In this article, we’ll explore what Fangji is, its potential uses, and the precautions you need to take before incorporating it into your wellness routine.

Fangji (Fourstamen Stephania Root)

What Is Fangji?

Menispermaceae family
image: Dinesh Valke

Fangji (防己), scientifically referred to as Stephaniae Tetrandrae Radix, is the dried root of a plant in the Menispermaceae family1. It is often derived from two main sources2:

The root itself is cylindrical, resembling a knotty, curved structure with a grayish-yellow surface. When cut, its interior reveals a white, powdery texture that often displays a spiderweb-like pattern. The herb has a bitter taste and a cold nature, which are key traits in traditional Chinese medicine (TCM).

Health Benefits of Fangji

Fangji has been traditionally valued for its ability to address a variety of health concerns. Below are some of its most notable benefits, supported by both ancient texts and modern pharmacological studies.

1. Reducing Swelling and Promoting Urine Flow

One of Fangji’s standout benefits is its ability to reduce water retention and promote diuresis (urine flow). This property makes it effective for treating conditions like3:

  • Edema (swelling caused by fluid retention)
  • Dysuria (difficulty urinating)
  • Beriberi (a disease caused by vitamin B1 deficiency, often accompanied by swelling and pain)

In TCM, Han Fangji is typically used for its strong ability to drain excess moisture and heat from the lower body. For instance, it is a key ingredient in Fangji Huangqi Tang, a traditional formula used to relieve water retention and strengthen the body45.

2. Alleviating Pain and Reducing Inflammation

This herb is also celebrated for its ability to relieve pain and reduce inflammation, making it a go-to remedy for conditions such as6:

  • Rheumatic pain
  • Joint stiffness
  • Arthritis

Modern pharmacological studies have shown that Han Fangji contains alkaloids like tetrandrine, which exhibit anti-inflammatory and analgesic (pain-relieving) properties7. These compounds help reduce swelling in joints and improve mobility, especially in cases of rheumatoid arthritis or gout8.

Interesting fact: In TCM, different types of Fangji are used based on symptoms. Han Fangji is preferred for water-related swelling, while Mu Fangji is more effective for pain caused by wind-damp obstruction9.

3. Lowering Blood Pressure

Research suggests that Han Fangji may have a hypotensive effect, meaning it can help lower blood pressure10. This is likely due to its ability to relax blood vessels and reduce vascular resistance. While promising, this benefit should be approached with caution, especially for individuals already on blood pressure medication.

4. Supporting Detoxification and Skin Health

Fangji is also used to treat eczemaboils, and skin infections. Its cooling and detoxifying properties make it ideal for clearing heat and toxins from the body11. For example, it may be combined with other herbs to address conditions characterized by redness, itching, or dampness on the skin12.

Risks and Side Effects

While Fangji offers numerous benefits, it is not without risks. Understanding its potential side effects is crucial before using it.

1. Toxicity Concerns

One of the most significant risks is associated with Mu Fangji, which comes from the Aristolochia family. This variety contains aristolochic acid, a compound known for its kidney toxicity and potential to cause cancer13. Due to these risks, Mu Fangji has been banned in several regions, including Taiwan and parts of Europe.

Important Note: When purchasing Fangji, ensure that it is Han Fangji (Stephania tetrandra) and not Mu Fangji (Aristolochia fangchi). Always check the source and consult a licensed practitioner.

2. Overuse and Dosage Issues

Excessive consumption of Fangji can lead to symptoms such as14:

  • Nausea
  • Vomiting
  • Muscle weakness
  • Tremors or spasms
  • Respiratory distress

In severe cases, overuse can cause paralysis or even death. For this reason, it is critical to adhere to the recommended dosage, typically 5–10 grams when used as a decoction15.

3. Not Suitable for Everyone

Fangji is not recommended for certain groups of people, including16:

  • Pregnant women: Its bitter and cold nature may pose risks to pregnancy.
  • Individuals with weak digestion: Fangji can harm the stomach and spleen if used excessively.
  • Those without damp-heat conditions: In TCM, Fangji is meant to address specific imbalances. Using it without proper diagnosis may worsen symptoms.

How to Use it Safely

If you’re considering Fangji, follow these tips to ensure safe use:

  1. Consult a Professional: Always seek guidance from a licensed TCM practitioner or healthcare provider.
  2. Choose the Right Type: Opt for Han Fangji and avoid Mu Fangji due to its toxicity.
  3. Stick to Proper Preparation: Fangji is traditionally used as a decoction (herbal tea). It should be boiled for at least 60 minutes to reduce potential side effects. Avoid grinding it into powder for oral consumption17.
  4. Monitor for Side Effects: If you experience nausea, vomiting, or other adverse symptoms, discontinue use and seek medical attention.

Final Thoughts

Fangji (Fourstamen Stephania Root) is a powerful herb with a rich history in traditional Chinese medicine. From reducing swelling to alleviating pain, it offers a wide range of benefits when used appropriately. However, it is not without risks, particularly when it comes to toxicity and misuse.

As with any herbal remedy, the key is balance. By consulting with professionals and using Fangji responsibly, you can enjoy its potential benefits while minimizing risks. After all, ancient wisdom combined with modern caution is the best way to harness the power of natural remedies.

Have you tried Fangji before? Share your experiences and thoughts in the comments below!

Trusted Sources

  1. https://baike.baidu.com/item/%E9%98%B2%E5%B7%B1/2204752 ↩︎
  2. https://yibian.hopto.org/db/?yno=108 ↩︎
  3. WANG Xiao-li, LIU Xiao, XIA Chun-yan, ZHU Ting-ting, ZHU Hui, CAI Bao-chang . Research progress in chemical constituents in single herbs of Fangji Huangqi Decoction and its pharmacological activities[J]. Chinese Traditional and Herbal Drugs, 2016, 47(19): 3527-3534 https://www.tiprpress.com/zcy/html/2016/19/20161928.htm ↩︎
  4. 张良, 江振洲, 卞勇, 等. 中药广防己与粉防己总提取物利尿效应及肾毒性比较研究[J]. 安徽医药, 2009, 13(12): 1471-1473. ↩︎
  5. https://sys01.lib.hkbu.edu.hk/cmed/mmid/detail.php?pid=B00055 ↩︎
  6. https://zh.wikipedia.org/zh-hans/%E7%B2%89%E9%98%B2%E5%B7%B1%E7%A2%B1 ↩︎
  7. https://www.sciencedirect.com/science/article/pii/S2095496421000017 ↩︎
  8. https://pmc.ncbi.nlm.nih.gov/articles/PMC5130046/ ↩︎
  9. https://sys01.lib.hkbu.edu.hk/cmed/mmid/detail.php?pid=B00055 ↩︎
  10. https://ccj.pku.edu.cn/Article/info?aid=271010315 ↩︎
  11. 陈奕君, 王伟, 肖红斌. 基于液相色谱-质谱联用的清肺排毒汤中痕量马兜铃酸 I 的监测及定量分析[J]. 药学学报, 2020, 55(8): 1903-1907. http://html.rhhz.net/YXXB/html/20200825.htm ↩︎
  12. https://www.tsumura.co.jp/chinese/brand/products/kampo/020.html ↩︎
  13. https://www.dh.gov.hk/textonly/chs/press/2004/040424.html ↩︎
  14. https://www.healthymatters.com.hk/zh/chinese-medicines/%E9%98%B2%E5%B7%B1-stephania-tetrandra-hong-kong/ ↩︎
  15. https://www.tph.mohw.gov.tw/?aid=86&pid=44&page_name=detail&iid=395 ↩︎
  16. https://m.baidu.com/bh/m/detail/ar_14245829734502123023(Zhang Ting, Associate Chief Physician, Department of Integrated Traditional Chinese and Western Medicine, The Third Xiangya Hospital of Central South University) ↩︎
  17. https://patents.google.com/patent/CN101468196B/zh ↩︎
Michael Zhang
Michael Zhang

Michael Zhang is a long-time health buff. He's committed to a lifestyle that's rooted in science. You can count on his articles to be accurate and reliable.

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