Guang Fang Ji, also known as Isotrema Fangchi, while having certain diuretic and other uses, has been banned due to containing the highly toxic component “aristolochic acid”.
Imagine a plant with a history steeped in traditional medicine, once hailed for its potential health benefits. Now, picture this same plant carrying a hidden danger, a risk so significant that it has been banned in several countries.
This is the story of Isotrema Fangchi, also known as Guang Fang Ji, a herb with a complex past and a cautionary tale for the present.
What is Isotrema Fangchi?
Isotrema Fangchi, or Guang Fang Ji, is a plant belonging to the Aristolochiaceae family. It’s native to regions of China and Vietnam, where it has been used in traditional Chinese medicine for centuries. Historically, it was believed to have diuretic properties and was used for various conditions, including weight loss, clearing lung heat, and postpartum recovery1.
The Dark Side of Guang Fang Ji: Aristolochic Acid
The reason behind Guang Fang Ji’s fall from grace is the presence of a potent toxin called aristolochic acid. This substance has been found to be highly nephrotoxic, meaning it can severely damage the kidneys. In some cases, it can even lead to kidney failure2.
But the dangers don’t stop there. Aristolochic acid has also been classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC)3. This means that there is sufficient evidence to conclude that it can cause cancer in humans, particularly cancers of the urinary tract4.
A History of Harm: The “Chinese Herb Nephropathy” Incident
The dangers of Guang Fang Ji came to light in the 1990s when a number of people in Europe developed severe kidney damage after taking a weight loss product that contained the herb5.
This incident, known as “Chinese Herb Nephropathy,” sparked global concern and led to the ban of Guang Fang Ji and other herbs containing aristolochic acid in many countries, including the United States and the European Union6.
Guang Fang Ji in Traditional Chinese Medicine: A Thing of the Past
Despite its historical use in traditional Chinese medicine, This herb is no longer considered safe for consumption. The risks associated with aristolochic acid far outweigh any potential benefits. In fact, the Chinese State Food and Drug Administration banned the use of it in the production of oral Chinese medicine products back in 20147.
Identifying Guang Fang Ji: A Matter of Importance
Guang Fang Ji can be identified by its distinct characteristics. It’s a perennial climbing vine with heart-shaped leaves and unique flowers. However, it’s crucial to note that identifying herbs based on visual appearance alone can be challenging. This is why it’s essential to consult with a qualified healthcare professional or a licensed herbalist before using any herbal remedies.
Warning: In traditional Chinese medicine, there are two herbs about Fang ji, Guang Fang Ji (banned and toxic) and Fen Fang Ji (widely used), but the average person may not be able to distinguish between them.
Safe Alternatives: Exploring Other Options
If you’re looking for natural remedies for any health concerns, it’s crucial to choose safe and effective alternatives. There are many other herbs and therapies in traditional Chinese medicine that do not carry the same risks as Guang Fang Ji. A qualified practitioner can help you explore these options and create a personalized treatment plan that is right for you.
Q&A: Addressing Your Concerns
- Q: Is Isotrema Fangchi still used in any traditional Chinese medicine practices?
- A: No, Isotrema Fangchi is banned in many countries8, including China, and is not considered safe for consumption due to the risks associated with aristolochic acid.
- Q: Can I still find products containing Isotrema Fangchi online or in some stores?
- A: While Isotrema Fangchi is banned, it’s possible that some products may still contain it. It’s crucial to be vigilant and carefully check the ingredients of any herbal products you are considering.
- Q: Are there any safe alternatives to Guang Fang Ji in traditional Chinese medicine?
- A: Yes, there are many other herbs and therapies in traditional Chinese medicine that are safe and effective. A qualified practitioner can help you explore these options.
The Bottom Line
The case of Guang Fang Ji serves as a stark reminder of the importance of prioritizing safety when it comes to herbal remedies. While traditional medicine has a rich history and can offer potential benefits, it’s crucial to be aware of the risks associated with certain herbs. Always do your research, consult with qualified professionals, and choose safe and effective alternatives whenever possible.
Trusted source
- https://baike.baidu.com/item/%E5%B9%BF%E9%98%B2%E5%B7%B1/61287318 ↩︎
- Yang HY, Chen PC, Wang JD. Chinese herbs containing aristolochic acid associated with renal failure and urothelial carcinoma: a review from epidemiologic observations to causal inference. Biomed Res Int. 2014;2014:569325. doi: 10.1155/2014/569325. Epub 2014 Aug 27. PMID: 25431765; PMCID: PMC4241283. https://pmc.ncbi.nlm.nih.gov/articles/PMC4241283/ ↩︎
- https://www.iarc.who.int/news-events/aristolochic-acid-associated-cancers-a-public-health-risk-in-need-of-global-action/ ↩︎
- Das, S., Thakur, S., Korenjak, M. et al. Aristolochic acid-associated cancers: a public health risk in need of global action. Nat Rev Cancer 22, 576–591 (2022). https://doi.org/10.1038/s41568-022-00494-x https://www.nature.com/articles/s41568-022-00494-x ↩︎
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7115735/ ↩︎
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4348117/ ↩︎
- https://www.nmpa.gov.cn/xxgk/fgwj/gzwj/gzwjyp/20040805010101598.html ↩︎
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4348117/ ↩︎
