- Research suggests “Zhe Beimu” (Fritillaria thunbergii) has benefits for cough, inflammation, and respiratory issues, supported by traditional and modern studies.
- It seems likely that risks include toxicity at high doses, with symptoms like breathing difficulties and tremors, requiring careful use.
- The evidence leans toward limited use in Western medicine, mainly in research, not standard practice.

Zhebeimu, also known as Chekiang Fritillary Bulb or Fritillariae Thunbergii Bulbus, is a time-honored herb in Traditional Chinese Medicine (TCM). Derived from the dried bulb of the Fritillaria thunbergii plant—a member of the lily family—this bitter, cooling herb has been used for over 2,000 years to soothe coughs, clear phlegm, and tackle inflammation.
But what does modern science say about it, and how does it fit into today’s health practices? Let’s break it down.
What Is Zhebeimu?

Zhebeimu (浙贝母 in Chinese) comes from the bulb of Fritillaria thunbergii Miq., a plant primarily grown in Zhejiang, China, though it’s also cultivated in Jiangsu, Anhui, and Hunan provinces. In TCM, it’s prized for its ability to “clear heat,” a concept akin to reducing inflammation or excess energy in the body, particularly in the lungs and heart. Picture it as a natural coolant for when your system’s overheating with coughs or sticky phlegm1.
The bulb is harvested in early summer, processed into forms like “big bulbs” (Da Bei), “pearl bulbs” (Zhu Bei), or sliced “Zhebeimu pieces” (Zhe Bei Pian), and often dusted with calcined shell powder to dry it out. Its appearance? Think crescent-shaped, pale yellow-to-white scales with a slightly bitter taste and a powdery texture when broken2.
Traditional Benefits and Uses of Zhebeimu
In TCM, Zhebeimu is a go-to for respiratory and inflammatory woes. Its key actions include:
- Clearing Heat and Phlegm: It’s used for coughs tied to “wind-heat” (think a warm, dry cough) or “phlegm-fire” (a wet, sticky cough)3.
- Detoxifying and Reducing Swelling: It tackles abscesses, sores, and swollen lymph nodes (scrofula)4.
- Soothing Lung Issues: From lung abscesses to breast swelling (mastitis), it’s a versatile remedy5.
Historical texts back this up. The Ben Cao Hui Yan (1624 AD) praises its ability to clear heat and disperse nodules, while the Ben Cao Gang Mu Shi Yi notes it “opens lung qi” for wind-heat-related lung troubles. Imagine it as a gentle broom sweeping away the gunk clogging your airways6.
Common TCM Uses
- Coughs: Paired with herbs like honeysuckle or mulberry leaf for wind-heat coughs, or fishy-smelling herb (Houttuynia cordata) for lung abscesses with bloody phlegm.
- Sores and Swellings: Combined with dandelion or seaweed to reduce toxic swellings or goiters.
- Dietary Boost: In China, it’s even a “food-medicine” ingredient, featured in recipes like Zhebeimu Almond Drink (see below).
Summary: Zhebeimu is important in TCM for respiratory and inflammatory problems. It clears heat and phlegm, detoxifies, reduces swelling, and soothes lung issues. It’s used in cough remedies, for sores, and even in dietary recipes.
What Does Modern Research Say?
Science is catching up to tradition, uncovering a range of potential benefits in Zhebeimu thanks to its 134+ chemical compounds7, including alkaloids like peimine and peiminine. Here’s what studies suggest:
- Cough Relief: Its antitussive (cough-suppressing) and expectorant (phlegm-clearing) effects are well-documented, making it a candidate for respiratory support (Natural drug sources for respiratory diseases from Fritillaria).
- Anti-Inflammatory Power: It may reduce inflammatory markers, potentially easing conditions like bronchitis or sore throats8.
- Cancer Potential: Early research, including a Chinese clinical trial, hints at its ability to combat multidrug-resistant leukemia9.
- Other Effects: Studies note antibacterial, pain-relieving, and even neuroprotective properties (Fritillariae Thunbergii Bulbus: Traditional Uses, Phytochemistry, Pharmacodynamics).
Think of Zhebeimu as a Swiss Army knife in herbal form—versatile, but still under the microscope for broader use.
Summary: Modern research on Zhebeimu, with over 134 chemical compounds, shows it may relieve coughs, fight inflammation, have potential against cancer, and possess antibacterial, pain – relieving, and neuroprotective properties, though more study is needed.
How Is Zhebeimu Used Today?
In TCM
- Dosage: Typically 5–10 grams boiled into a decoction (soup), though it’s also ground into powders or pills.
- Formulas: It’s a star in blends like Jin Bei Tan Ke Qing (for phlegm-heat coughs) or Nei Xiao Luo Li Pian (for scrofula).
- External Use: Crushed bulbs are applied to sores or abscesses10.
In the Kitchen
As a “food-medicine” approved by China’s health authorities, Zhebeimu pops up in simple recipes:
- Zhebeimu Almond Drink: Boil 10g Zhebeimu with 8g sweet almonds and 15g rock sugar for 30 minutes. Cool and sip for a cough-soothing treat.
- Zhebeimu Egg: Mix 2–3g powdered Zhebeimu into an egg, steam it, and eat daily for a week to ease phlegm.
In the West
Western medicine hasn’t fully embraced Zhebeimu—it’s mostly a research subject rather than a pharmacy staple. However, its global trade (e.g., to Europe and Korea) and studies on its anti-cancer and anti-inflammatory effects signal growing curiosity (Efficacy, chemical composition, and pharmacological effects).
Summary: Zhebeimu is used in TCM in decoctions, formulas, and externally. It’s also used in Chinese kitchen recipes. In the West, it’s mainly a research topic, but its global trade and studies on its effects show growing interest.
Risks and Safety Tips
Zhebeimu isn’t without its cautions. High doses can spell trouble11:
- Toxicity Signs: Animal studies show breathing issues, tremors, or dilated pupils at excessive levels (Acute and sub-chronic toxicity studies).
- Drug Interactions: Avoid mixing it with herbs like aconite (Chuan Wu or Fu Zi), which could amplify side effects.
- Who Should Skip It? Pregnant or breastfeeding women and kids should consult a doctor first.
The takeaway? Use it wisely—preferably under a TCM practitioner’s guidance—to keep the benefits outweighing the risks.
How to Spot Quality Zhebeimu
Look for12:
- Color: White to pale yellow, with a powdery coating.
- Texture: Hard, brittle, with a starchy white interior.
- Taste: Slightly bitter, with a faint aroma.
Compared to its cousin, Chuanbeimu (from Fritillaria cirrhosa), Zhebeimu is bitter and excels at clearing thick phlegm, while Chuanbeimu is sweeter and better for dry, chronic coughs.
Quick Q&A
Q: What’s the difference between Zhebeimu and Chuanbeimu?
A: Zhebeimu (bitter, cooling) targets thick, heat-related phlegm; Chuanbeimu (sweet, mild) soothes dry, chronic coughs. Both reduce swelling, but Zhebeimu’s stronger at it.
Q: Can I use Zhebeimu daily as a food?
A: Yes, in small, approved amounts (like in recipes), but don’t overdo it—stick to TCM guidelines.
Q: Is Zhebeimu safe for kids?
A: Only under a doctor’s supervision, as kids’ systems are more sensitive.
The Bottom Line
Zhebeimu, or Chekiang Fritillary Bulb, blends ancient wisdom with modern promise. From easing coughs and swelling in TCM to showing anti-cancer potential in labs, it’s a fascinating herb with a lot to offer—if used carefully. While it’s not a household name in Western medicine yet, its rich history and emerging science make it worth watching. Want to try it? Talk to a TCM expert to see if it’s right for you—and maybe whip up a soothing almond drink while you’re at it.
Trusted Source
- https://sys01.lib.hkbu.edu.hk/cmed/mmid/detail.php?pid=B00124 ↩︎
- https://baike.baidu.com/item/%E6%B5%99%E8%B4%9D%E6%AF%8D/1110619 ↩︎
- 陈遇英.浙贝母的产地加工与质量[J].基层中药杂志, 1999(01):13.DOI:CNKI:SUN:JZZY.0.1999-01-011. ↩︎
- 李志忠,马吉安,郭志云.一种用于治疗尖锐湿疣的中药组合物及其制备方法:CN202011248722.0[P].CN112386668A[2025-03-18]. ↩︎
- 李小伟.用于治疗肺脓肿的中药药物:CN201610127309.6[P].CN105663899A[2025-03-18]. ↩︎
- https://www.zysj.com.cn/zhongyaocai/zhebeimu/index.html ↩︎
- https://pubmed.ncbi.nlm.nih.gov/30987173/ ↩︎
- 张明发,沈雅琴,朱自平,等.浙贝母的抗炎和抗腹泻作用[J].湖南中医药导报, 1998, 4(10):2.DOI:CNKI:SUN:HNZB.0.1998-10-020. ↩︎
- 胡凯文,陈信义,左明焕,等.浙贝母逆转白血病(肿瘤)细胞耐药的临床与实验研究[J].中国医药学报, 2004. ↩︎
- https://www.baidu.com/bh/dict/ydyp_15943451651697537739?contentid=ydyp_15943451651697537739&query=%E6%B5%99%E8%B4%9D%E6%AF%8D&sf_ch=ch_search_5713&sf_ref=search&subTab=%E7%94%A8%E8%8D%AF%E8%AF%B4%E6%98%8E&from=dicta&isPageHome=1 ↩︎
- https://m.baidu.com/bh/m/detail/ar_9030174998244658216(Bai Wenwu, Deputy Chief Physician, Department of Traditional Chinese Medicine, Qilu Hospital of Shandong University) ↩︎
- https://www.ucn.org.hk/zh-hans/health-education/health-article/cm-health-tips-55/?back=/en/health-education/health-article/?page=25 ↩︎